Whole-body MRI (WB-MRI) may improve ALS diagnostic certainty. WB-MRI assesses muscle swelling (edema) as a marker for lower ...

Oral PrimeC for ALS significantly reduced toxic TDP-43 protein levels in a Phase 2b trial. PrimeC also slowed functional decline and extended survival by about 15 months. The treatment was well ...

Nura Bio raised $73.8 million to advance two experimental SARM1 inhibitors. The therapies are designed to block SARM1, a ...

Former Tennessee Titans football player Chris Johnson is sharing his diagnosis with ALS at age 39. The ex-NFL player says he hopes to raise awareness and encourage testing for the rare disease.

Having resilience is so important to me that I’ve written several columns about it. I believe resilience — the ability to cope with and survive change — is a skill ALS patients should hone to navigate ...

Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease characterized by the progressive loss of motor neurons, nerve cells that control the voluntary muscles. This leads to overall ...

TRCN-1023, an experimental treatment for ALS, aims to restore UNC13A function. It is designed to improve communication between nerves and muscles. Global Phase 1/2 clinical trials are underway to ...