The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's ...

Regulatory mechanisms governing stem cell quiescence in glandular organs remain ill-defined. Here, multi-omics profiling ...

Biomedical research typically follows a familiar path: developing treatments that block, enhance or mutate certain signaling pathways, genes or proteins to change the function of different cells in ...

Naturally occurring calcium channels act as pores on the membranes of excitable cells, such as those found in nerves and muscles. The channels drive electrical activity by controlling the influx of ...

Cutaneous squamous-cell carcinoma (SCC) is primarily caused by oncogenesis mediated by ultraviolet radiation, and β-human papillomavirus (β-HPV) is believed to be a mere facilitator that is ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...