T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

There is a high unmet need for accessible, affordable, and high-quality fertility care, as approximately 1 in 6 people are affected by infertility worldwide. While meiotic failure is a major cause of ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

An iron-sensing tool lets researchers watch stem cells transition in real time, linking iron dynamics to the earliest decisions in cells. Study: The genetically encoded biosensor FEOX is a molecular ...

Japanese researchers discovered that hair graying and melanoma share a surprising cellular origin. When DNA damage strikes melanocyte stem cells, they may undergo a protective process called ...