Michael Buck, PhD, professor of biochemistry in the Jacobs School, recently received NIH funding to explore how molecular readers of DNA access and activate seemingly hidden genes.

Transcription factors are the most powerful genes in our body. They are master regulators and have been implicated in our biggest diseases, even aging itself. Yet, many in the pharmaceutical industry ...

Every cell in the body has the same DNA, but different cell types—such as muscle or brain cells—use different parts of it.

Northwestern Medicine scientists have discovered how a specific transcription factor promotes genetic reprogramming and ...

Researchers uncovered 117 enzymes that modify RNA polymerase II, the key enzyme that transcribes DNA into RNA. The study ...

Findings suggest maternal T1D exposure leads to protective epigenetic alterations in children, influencing immune response ...