A large-scale genomic study by researchers at Central South University and King’s College London reveals that rare and common genetic risks interact antagnistically to maintain healthy telomere length ...

The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, ...

New findings describe how the enzyme CST is recruited to the end of the telomere, where it maintains telomere length with the help of subtle chemical changes made to the protein POT1. The length of ...

Longer leukocyte telomere length is associated with higher left ventricular mass (LVM) and larger global ventricular size, as well as better cardiac function and lower risk of heart failure (HF). The ...

Telomere length can be used in the diagnosis of interstitial lung diseases like idiopathic pulmonary fibrosis, but it likely also has therapeutic implications, according to a new report. Mounting ...

Regular aerobic exercise later in life prevents genomic instability characterized by DNA damage and telomere dysfunction, according to a study from the Department of Internal Medicine at the ...

A study reveals that a protein called RPA is essential for maintaining chromosome stability by stimulating telomerase. New findings from the-Madison suggest that problems with a key protein that helps ...

CST (purple/lavender) bound to POT1 (red). Phosphorylation of the crimson-highlighted region in POT1 regulates the recruitment and activity of CST–Polα-primase at telomeres. The length of telomeres ...