T cell-dependent and T cell-independent primary class-switch DNA recombination (CSR)-inducing stimuli induce activation-induced cytidine deaminase (AID) in a B cell differentiation stage-specific ...

As it fights off an infection, the human body tailors its immune response. For example, in a process known as class switch recombination, immune cells called B cells rearrange their DNA. In so doing, ...

The discovery of activation-induced cytidine deaminase (AID) has revealed that there is a molecular link between two apparently different genetic alteration events — class-switch recombination and ...

In a recent study posted to the medRxiv* preprint server, researchers reported a class switch in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibodies due to repeated ...