The risk for hyperkalemia was highest with use of steroidal MRAs in combination with other RAASi. In patients with diabetic kidney disease, use of 2 classes of renin-angiotensin-aldosterone system ...
At one time, dual RAAS blockade was expected to provide more-complete inhibition of RAAS among patients with DKD. Results of large clinical trials dashed these hopes, finding increased risk of AKI and ...
Renin–angiotensin system (RAS) inhibitors — including angiotensin-converting–enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) — slow the progression of mild or moderate chronic kidney ...
SELECT was a large study focused on obesity and cardiovascular disease in people without type 2 diabetes, but it included ...
Use of the antihypertensive medications improved survival whether or not patients fully recovered from acute kidney injury. Initiating or resuming renin-angiotensin-aldosterone system (RAAS) blockade ...