Pharmaceutical Technology on MSN

RNA-targeting small molecules: A new frontier of drug discovery

With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology advances.
EurekAlert!

University of Barcelona team describes new biochemistry for RNA at low temperatures

An artistic representation of the temperature dependence of the RNA free-energy landscape (FEL) of folding. The authors showed that RNAs undergo a phase transition in the cold and misfold due to the ...

RNA is key to the dark matter of the genome - scientists are sequencing it to illuminate human health and disease

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint ...
Phys.org

RNA in action: Filming ribozyme self-assembly

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...
Newsweek

Evolution Mystery’s Answer May Be Hidden in Rain

Scientists may have a step forward in understanding how life on our planet came to exist. The mystery of how tiny molecules of RNA came to be enclosed within membranes, forming the very first cells, ...
News Medical

Researchers capture a ribozyme in motion for the first time

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...
Nature

Targeting RNA and RNA-Binding Proteins: development of chemical probes and therapeutics

Many essential biochemical processes in cells in various life forms involve RNA molecules, which are critical for development, proliferation, homeostasis, immune defense, intercellular communication, ...
BioTechniques

Lights, camera, action: molecular film captures an RNA molecule building itself

Researchers have visualized how a large RNA molecule assembles itself into a functional machine. RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like ...
CU Boulder News & Events

Here’s what a Nobel Prize-winning scientist wants you to know about the Covid-19 vaccines and the future of RNA

Dr. Thomas Cech, Nobel Laureate, in an interview with CNN, provides insight into how RNA has impacted modern medicine and biology and how mRNA, holds promise for future vaccines and other scientific ...
insider.si.edu

The RNA world : the nature of modern RNA suggests a prebiotic RNA / edited by Raymond F. Gesteland, Thomas R. Cech, John F. Atkins

Before RNA and after : geophysical and geochemical constraints on molecular evolution / Stephen J. Mojzsis, Ramanarayanan Krishnamurthy, and Gustaf Arrhenius -- Prospects for understanding the origin ...