In neurodegenerative diseases, microglia can help or harm the brain. In the October 3 Journal of Clinical Investigation, scientists led by Ilia Baskakov at the University of Maryland School of ...

The study reveals that hippocampal microglia actively regulate adult neurogenesis. When TGF-beta signaling is absent, ...

A researcher with the Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases at UT Health San Antonio has ...

Parkinson's disease is characterized by the progressive loss of dopaminergic neurons in a specific brain region known as the substantia nigra. This neuronal degeneration is closely linked to ...

Add Yahoo as a preferred source to see more of our stories on Google. Microglial receptor ADGRG1 helps immune cells eat amyloid plaques and may offer new hope for Alzheimer's treatment. (CREDIT: ...

SAN FRANCISCO—In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein—the most important genetic risk ...

Genetic neurodegenerative disorders like Tay-Sachs and Sandhoff disease currently have no effective treatments. A possible strategy is replacing affected cells with healthy ones in order to slow the ...

In healthy rodent brains, newborn neurons are constantly generated in the stem cell niche, known as the subventricular zone (SVZ). These cells might help to repair a brain that has been damaged by ...

Breakthrough research from the University of Cincinnati College of Medicine is revealing how immune cells in the adult brain can regulate the generation of new neurons.