Researchers have created a deep learning pipeline for designing soluble analogues of key protein structures used in pharmaceutical development, sidestepping the prohibitive cost of extracting these ...

Understanding the best ways to get a membrane protein to its destination in a cell is crucial, and the best method to make this happen is still unclear. Cell-free systems allow for interactions ...

Membrane proteins are crucial for numerous biological processes and serve as important drug targets. For decades, scientists have relied on detergents to extract membrane proteins from cell membranes ...

In the evolutionary history of life, the ability of a cell to separate its inner world from the external environment was an important turning point. The so-called plasma membrane lets cells control ...

Proteins are building blocks of our bodies, but they do not work solo. They form partners to facilitate in different biological processes that keep us going. However, analyzing how proteins interact ...

GPCRs (G-protein-coupled receptors) represent the largest family of membrane receptors currently targeted by approved drugs. It is estimated that approximately 700 approved drugs target GPCRs ...

Nuclera, the biotechnology company enabling rapid access to high-quality proteins, today announced the launch of its nanodisc panel to support screening and scale-up of G-Protein Coupled Receptors ...

For centuries, coronaviruses have triggered health crises and economic challenges, with SARS-CoV-2, the coronavirus that spreads COVID-19, being a recent example. One small protein in SARS-CoV-2, the ...