Researchers use mass spectrometry-based methods for single-cell proteomics, where they can identify and quantify thousands of proteins, proteoforms, and post-translational modifications within each ...

To identify specific chemicals or molecules in the life sciences and medical research, scientists often use mass spectrometry (MS), usually paired with liquid chromatography (LC). These technologies ...

Disulphide bonds play a critical role in stabilising the three‐dimensional structures of proteins and ensuring their correct function. Their precise mapping is essential not only for understanding ...

Insights from IndustryJose-Castro-PerezVice President, Product ManagementSCIEX In this interview, we sit down with Jose Castro-Perez, Vice President of Product Management at SCIEX, to discuss his ...

For biologists, seeing is believing. But sometimes biologists have a hard time seeing. One particularly vexing challenge is seeing all the molecules in an intact tissue sample, down to the level of ...

A new tissue expansion method enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations. For biologists, ...

Laura-Isobel McCall, Ph.D., and Zhibo Yang, Ph.D., co-principal investigators and associate professors of chemistry and biochemistry in the Dodge Family College of Arts and Sciences at the University ...

Leiden researchers, led by Sebastian Pomplun, have developed a new method to screen hundreds of thousands of molecules for ...

Native mass spectrometry that targets the blue component of blue-green algae has been found to be more sensitive to potentially toxic blooms than current techniques. Researchers at the University of ...