Monomeric CRISPR-Cas9 nucleases are widely used for targeted genome editing but can induce unwanted off-target mutations with high frequencies. Here we describe dimeric RNA-guided FokI nucleases (RFNs ...
Figure 1: Architectures of Cas9 and FokI-dCas9 fusion variants. We chose two sets of sgRNA binding-site pairs with different orientations within GFP. One set placed the pair of NGG PAM sequences ...
On the grounds of Roland Garros this week, a Spanish terrier-bulldog mix has been turning heads and warming hearts. They call him Foki. He’s anything but poky when darting around the court chasing ...
Developments in molecular diagnostics have been vital in discovering novel pathogens and diagnosing many human diseases. The recent coronavirus 2019 (COVID-19) pandemic, caused by severe acute ...
Menstrual status and lung cancer in female patients from the Spanish WORLD07 database. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I. This abstract does not include a full text ...
Designer Adika Titut Triyugo has come up with an innovative design concept to help with your household chores, the Foki Vacuum footwear. The idea behind the design allows you to do multiple tasks at ...
They may not be the first vacuum shoes to emerge in concept form, but these so-called Foki shoes from designer Adika Titut Triyugo are certainly the most stylish -- at least in an ASIMO chic sort of ...
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