After a long search, RIKEN researchers have identified an enzyme crucial for keeping lipid-linked sugar chains in check in yeast cells. This finding, published in the Journal of Cell Biology, reveals ...

In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists have now derived universal rules to enable the de novo design of optimal enzymes. As an example, they ...

Tilting the scales at 4.7 megadaltons and reaching 1 micron in length, the newly discovered algal enzyme PKZILLA-1 is the largest protein ever identified in biology. Indeed, PKZILLA-1 is 25% larger ...

From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as ...

Usually enzyme complexes make multistep processes easier by catalyzing sequential reactions in which the product of one enzyme becomes the substrate for the next. In a new finding, researchers report ...

NUDT5 enzyme acts as a molecular scaffold that maintains metabolic balance. Inside every cell, a finely tuned metabolic network determines when to build, recycle or stop producing essential molecules.

Cytochrome P450 enzymes constitute a vast and diverse superfamily of haem‐containing proteins that orchestrate a broad array of oxidative reactions. Their inherent versatility enables them to catalyse ...

Hydrophilic and hydrophobic molecules tend to avoid each other. But phosphoglycosyl transferases, enzymes that reside on bacterial cell membranes, can bring these odd couples together and catalyze ...

Plastic waste build-up in the environment is an enormous ecological challenge. Indeed, 40% of plastic waste goes around collection systems and ends up residing in natural environments. Polyethylene ...

Researchers developed C28, an engineered polymerase that efficiently synthesizes RNA at near-natural speeds with high accuracy. Created through directed evolution, the enzyme also performs reverse ...

Enzymes all have specific purposes and capabilities. Time to learn about them.