Table 1 Structural comparison of different self-assembling proteins; size was measured from the longest axis while # subunits indicate the number of monomers within the nanoparticle. Fused subunits ...

Antigen loading onto class I major histocompatibility complex (MHC-I) proteins relies on chaperones and protein flexibility. Researchers now provide new insight into the process, especially for the ...

Antigens are a critical part of how the immune system works; they are present on many types of cells, and can be made of proteins, lipids, sugars, and other substances. Antigens are presented to ...

ROS are key players in the immune system's response to infection and cancer, influencing how the body identifies and fights these threats. A balanced level of ROS supports healthy immune function, but ...

A new discovery about how cells communicate with each other in the body’s immune system has revealed deeper insights for an international team of scientists into fundamental immune system function.

Researchers at Children’s Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule known as TAPBPR that optimizes the binding and presentation of foreign antigens across the ...