Nucleic acid synthesis underpins life’s vital processes, from replication and transcription to the regulation of gene expression, while polymerase enzymology explores the molecular mechanisms by which ...

Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid ...

The raw material for de novo fatty acid synthesis is acetyl-CoA, which can be obtained via the citrate shuttle pathway or from acetic acid. ACC and FASN catalyze the conversion of acetyl-CoA into ...

Liver is the major organ for metabolism of sulfur amino acids (methionine, cysteine, taurine) and expresses high levels of sulfur amino acid synthesis and metabolising enzymes. Dietary intake, ...

From legacy therapeutics to next-generation GLP-1s, advances in synthesis, analysis, and regulation are reshaping how peptide ...

Rolls of brightly colored plastic. After it is used and discarded, polylactic acid could be used as a feedstock for making the amino acid alanine. Credit: Shutterstock One of the simpler amino acids, ...